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Patients assigned to tirzepatide showed a 20.9% BW loss after 36 weeks with an additional 5.5% reduction after 52 weeks, while those who switched to placebo experienced a 14% weight regain, confirming the findings from STEP 4 supporting the chronicity of obesity and the need for continuous treatment

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Similar to the time course of neuronal activity in the cerebellar nuclei, temporally specific periodic signals predicting event timing have also been reported in the beta-band coherence of neuromagnetic activity between the cerebellum and the cerebral cortex when listening to an auditory beat [353], suggesting that such signals may provide a basis for the perception of rhythms